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Advancing Hydrocephalus Care Through Innovation

Anuncia Medical is a medical technology company dedicated to improving the care and management of cerebrospinal fluid (CSF) disorders.

Our name is inspired by Panthera Uncia, the snow leopard, known in Asia as the “Guardian of the Headwaters”. We believe that protecting the body’s “headwaters,” the flow of cerebrospinal fluid, is essential to protecting quality of life.

Through close collaboration with neurosurgeons, engineers, researchers, patients, and caregivers, we develop technologies designed to support clinicians, reduce the burden of care, and improve confidence for families navigating complex neurological conditions. Our mission is to help safeguard the flow of CSF, empowering both healthcare providers and caregivers with solutions that support better outcomes and greater peace of mind.

Elderly man kisses smiling elderly woman as they hold coffee mugs in a cozy kitchen.
Smiling family with father sitting on floor holding son on shoulders and mother beside them on sofa.
Happy elderly couple dancing together inside a cozy home, smiling and holding hands.
Smiling mother and father embrace their young child outdoors in golden sunlight.
Elderly man kisses smiling elderly woman as they hold coffee mugs in a cozy kitchen.
Smiling family with father sitting on floor holding son on shoulders and mother beside them on sofa.
Happy elderly couple dancing together inside a cozy home, smiling and holding hands.
Smiling mother and father embrace their young child outdoors in golden sunlight.
Abstract curved light waves with blue, purple, pink, and orange hues on white background.

Shunt Occlusion Remains the Biggest Obstacle in Hydrocephalus Currents.

For many individuals living with hydrocephalus, shunt systems are critical for maintaining the balance of cerebrospinal fluid within the brain. Shunt malfunction remains common, with ventricular catheter occlusion persisting as the leading cause of failure.

When blockages occur, patients often require surgical revision to restore flow. These revision surgeries place significant burdens on patients and families while creating additional challenges for clinicians managing long-term care.

Addressing proximal catheter occlusion proactively represents one of the most important opportunities for improving hydrocephalus treatment.

Medical professional with patient

Introducing the
ReFlow® Mini Flusher
.

The ReFlow® Mini Flusher was developed to provide a noninvasive method to maintain, increase or restore CSF flow through a ventricular shunt catheter.

Integrated as part of the shunt system, the device allows trained patients, caregivers and clinicians to deliver a controlled flush down the ventricular catheter toward the inlet flow holes to maintain patency. This maintenance approach provides a new option for managing proximal obstruction and potentially avoiding the need for surgical revision.

Beyond acute intervention, the ReFlow® Mini Flusher introduces a new level of control in how clinicians approach shunt management by offering the ability to actively engage with the system on a regular basis. This capability supports efforts to maintain flow and provide an additional layer of confidence in managing complex hydrocephalus patients.

Developed on concepts from Dr Joseph Madsen at Boston Children’s Hospital and in collaboration with neurosurgeons and engineers, the ReFlow is the result of focused effort to address the most common and persistent failure in hydrocephalus shunts.

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Transparent plastic inline switch with two connected cables on a white background.
• Designed to address ventricular catheter occlusion
• Compatible with any shunt valve or catheter system

Purpose Driven Innovation

Our Mission

To advance cerebrospinal fluid management through responsible innovation that supports clinicians and improves the lives of patients living with hydrocephalus.

doctor
Snow leopard mascot, the Guardian of the Headwaters

Our Story

Anuncia is named after the “Guardian of the Headwaters”, Panthera uncia, more commonly known as the snow leopard. Snow leopards live in mountainous regions of Asia and roam the headwater areas.

Future Planning

We are committed to evolving the ReFlow® platform to further support clinicians and improve hydrocephalus and neurocritical care.

doctor

Grounded in
Clinical Need.

The development of our ReFlow® platform has been guided by real-world clinical challenges and ongoing collaboration with neurosurgical professionals.

Each stage of innovation is informed by patient outcomes, published research, and a commitment to improving the management of fluid systems in practice.

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FDA Cleared
Breakthrough Device Designation for ReFlow Mini Flusher
Up to 40%
Of hydrocephalus shunts require revision within the first year, historically¹
4+ Years
Clinical follow-up data informing the development of the ReFlow platform
Year 1Year 2Year 3Year 4
10+ Years
Technology development through collaboration with neurosurgeons, scientists and engineers

1 Browd SR, et al. Failure of Cerebrospinal Fluid Shunts: Part I: Obstruction and Mechanical Failure. Pediatric Neurology. 2006;34(2):83–92.